UPSC Mains 2017 Medical Science Optional Paper I questions

40 questions from the Civil Services (Main) Examination 2017. Official UPSC paper (PDF) · All Medical Science Optional PYQs

1. Write in short about Embalming.

   10 marks

2. Describe microscopically, the cellular components of lungs. Add a note on fetal distress syndrome.

   10 marks

3. Describe the developmental component and nerve supply of the tongue.

   10 marks

4. Describe the functions of spinocerebellum.

   10 marks

5. Tabulate the findings of various biochemical tests in blood and urine of patients of pre-hepatic, hepatic and post-hepatic jaundice.

   10 marks

6. Describe how iron is absorbed, transported and stored in our body. Give the different tests done to assess status of iron in the body.

   20 marks

7. Enumerate the sites for formation of erythrocytes in the embryo, foetus and adults.

   5 marks

8. Describe the characteristic changes in the cytoplasm and nucleus during erythropoiesis.

9. Describe in detail about hepatic spaces in relation to peritoneal reflection. Add a note on its applied importance.

   10 marks

10. Describe blood supply of brain stem and add a note on its applied importance.

11. Describe the functions of basal ganglia in voluntary actions.

    10 marks

12. Compare the functions of basal ganglia with primary cortex.

    10 marks

13. Describe the gross anatomy, innervation and applied importance of the urinary bladder. Add a note on autonomous bladder.

    15 marks

14. Discuss the principle of 'Polymerase Chain Reaction (PCR)' technology - and outline the steps involved. Write its clinical application.

    15 marks

15. Describe the shoulder joint under the following headings

    15 marks

16. Give the anatomic basis of black eye.

17. Show the sucking reflex through a diagram. Describe positive and negative feedback actions of estrogen.

    8 marks

18. Describe baroreceptor reflex mechanism in the regulation of blood. pressure.

19. Justify the statement 'Vitamin D is a hormone'. Describe the synthesis, mechanism of action and physiological functions of vitamin D.

    15 marks

20. Define neoplasm. List five differences between benign and malignant

21. Explain the challenges in epidemiology and control measures in malaria. Discuss its laboratory diagnosis.

    10 marks

22. Discuss acute paracetamol poisoning emphasizing on mechanism of toxicity and its treatment.

    10 marks

23. Describe the gross and microscopic appearance of post-primary tuberculosis of lung.

    10 marks

24. How will you assess that the injury is 'Grievous Hurt' as per Section 320 of the Indian Penal Code? Illustrate with examples.

    10 marks

25. Describe the gross and microscopic features of acute proliferative glomerulonephritis.

26. Describe in brief the etiopathogenesis of squamous cell carcinoma of cervix.

    10 marks

27. Describe the mechanism of action of sulfonamides. Also describe which methods bacteria employ to develop resistance to it.

    15 marks

28. What are the factors responsible for invasive candida infection. Briefly describe the laboratory diagnosis of bloodstream candida F infection.

29. Name opportunistic fungal (two) and parasitic (two) agents causing infections in an HIV patient. Describe the laboratory, diagnosis of any one of them.

    5 marks

30. A 16-year-old girl has been brought for medical examination to the hospital by the police with alleged history of rape. How will the medical officer proceed to examine her? Describe the possible findings. What are the specimens preserved to establish the alleged crime?

    20 marks

31. Discuss the clinical features, management and post-mortem findings in a case of cyanide poisoning.

    15 marks

32. Explain the reasons for the following

33. Beta blockers should not be given with Verapamil.

    5 marks

34. Discuss the pathogenesis of enteric fever. What are the different. mechanisms by which salmonella acquires antimicrobial resistance?

    10 marks

35. Define immunological tolerance and discuss its role in autoimmunity, with one example.

    10 marks

36. A 40-year-old chronic alcoholic male presents himself with ascites, splenomegaly, jaundice and hematemesis.

37. What is the likely disease in the liver?

38. What is the reason for hematemesis?

39. Describe the gross and microscopic features of the liver in this case.

    10 marks

40. Discuss briefly the mechanism of action, uses and side effects of the following

    15 marks