UPPSC PCS - 2016

Which of the following pairs is incorrectly matched?

Year Asked: 2016

A
Thiamine - Beriberi
B
Ascorbic acid - Scurvy
C
Vitamin K - Blood clotting
D
none of the above

Correct Answer

D. none of the above

Detailed Explanation

The correct answer is D. All three pairs are correctly matched, so the question has no incorrect pair.

  • Thiamine (B1) and beriberi: Thiamine is a coenzyme in carbohydrate metabolism (as TPP). Its deficiency causes beriberi, which affects the nervous and cardiovascular systems. Polished rice was a classic source of this deficiency.
  • Ascorbic acid and scurvy: Vitamin C is needed for hydroxylation of proline and lysine during collagen synthesis. Deficiency weakens connective tissue, causing spongy gums, bleeding and poor wound healing.
  • Vitamin K and blood clotting: Vitamin K is needed for the gamma-carboxylation of clotting factors II, VII, IX and X, and of proteins C and S. Deficiency causes a bleeding tendency, including haemorrhagic disease of the newborn.

The core concept is micronutrient deficiency diseases, which fall under human physiology and nutrition in the General Science syllabus. For Mains GS-II, link this to public health and nutrition programmes such as fortification and the Poshan Abhiyaan.

Trap: Aspirants often assume a question with "none of the above" must hide a trick and start hunting for an error that isn't there. Check each pair against the exact deficiency disease and function. If all three hold, D is the answer.

This question appeared in UPPCS 2016 GS Paper 1.

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